Trenbolone is a very well-known injectable anabolic steroid, and milligram for milligram it is the most powerful anabolic steroid commercially and conventionally available. It is an anabolic steroid that tends to invoke both intimidation as well as amazement among those who read about it. The truth is that although Trenbolone is not as harsh of an anabolic steroid as many make it out to be, it is by no means a beginner compound and does need to be taken seriously when the use of it is considered. It is typically used by intermediate to advanced level anabolic steroid users, and seldom used by beginners until several cycles of experience has been built up.
Trenbolone is a derivative of Nandrolone (Deca-Durabolin), and alongside Nandrolone, is in the family of anabolic steroids known as 19-nor compounds. This category of 19-nor steroids is named as such due to the fact that these compounds contain a specific alteration at the 19thcarbon on the anabolic steroid’s molecular structure. This alteration, which is the removal of the 19th carbon, is not seen in any other anabolic steroid classes. It also contains other alterations in this area that grant it enhanced androgenic strength (its ability to bind at a much greater strength to the androgen receptor), as well as a high degree of resistance to metabolic breakdown within the body.
Trenbolone, as a result, expresses five times the androgenic and anabolic strength of Testosterone, with a rating of 500 for each. It also expresses characteristics that grant it the ability to promote weight gain with nearly all of it being muscle mass, and no water retention. Trenbolone has also been found to stimulate endogenous production of the very anabolic hormone IGF-1 (Insulin-like Growth Factor 1) in muscle tissue, adding to its anabolic capabilities. Ultimately, the reason for Trenbolone’s inability to make the user hold onto water and become bloated is due to the fact that its chemical modifications render it unable to aromatize into Estrogen at any dose what so ever.
Three major esterified forms of Trenbolone exist: Trenbolone Acetate, Trenbolone Enanthate, and Trenbolone Hexahydrobenzylcarbonate. The most popular and most widely used of the three is the fast-acting acetate variant. Trenbolone’s history generally begins in 1967, where it was studied repeatedly in France by Roussel-UCLAF. It was eventually picked up by Hosescht in England and manufactured in its acetate ester format, and sold under the brand name of Finajet. In France, Roussel marketed it as Finaject. Both companies were in reality owned and operated by Roussel AG of Germany. Both brand names of the same product (Trenbolone Acetate) were used on the prescription drug market as human grade medicines before they were discontinued and disapproved for use in humans towards the 1980s. Trenbolone Hexahydrobenzylcarbonate was sold under the brand name Parabolan as well during this time before encountering the same fate as the other two in the 1990s.
Today, Tren remains officially utilized as a veterinary drug, mostly in the application of promoting mass in cattle used to provide food. It remains a peculiar compound of interest to the medical establishment, however, as scientific studies continue to continue with Trenbolone, with scientists discovering new applications for human use and recommending its re-introduction as a human grade medicine. To date, however, Trenbolone is still unapproved for human use by the FDA and all current Trenbolone products are generally underground lab (UGL) products.
Chemical Characteristics of Trenbolone
Trenbolone is essentially a derivative of Nandrolone with some very significant differences in its chemical properties and strength. Trenbolone and its parent hormone Nandrolone both belong to a class/category of anabolic steroids known as 19-nor compounds, or 19-nors (short for 19-nortestosterone). 19-nor anabolic steroids are labeled as such because they lack the 19th carbon on their structure – this carbon exists on Testosterone and all other anabolic steroids with the exception of 19-nor compounds, such as Nandrolone and Trenbolone. This significantly changes around the properties of an anabolic steroid and makes it a Progestin, which will be discussed further shortly. In Trenbolone, this missing carbon atom at the 19th position (which is in reality a whole methyl group) is replaced by double-bonds between the two carbon atoms that the 19th carbon was originally bound with (this differs from Nandrolone where the lacking 19th carbon is simply replaced with a hydrogen atom instead of double-bonds in Trenbolone’s case). This lack of a 19th carbon is what makes 19-nor compounds very resistant to the aromatase enzyme and therefore very resistant to any estrogen conversion – however, this is not the whole story for Trenbolone when it comes to aromatization. Trenbolone also contains modifications at carbons 19 and 11, where one hydrogen atom was removed from each carbon so that carbons 19 and 11 become double-bonded with their neighboring carbon atoms in their respective cycloalkane rings. It is these additional modifications of double-bonds at carbon 19 and 11 that grant Trenbolone to be not just resistant to aromatization, but to become completely immune to it and be unable to interact what so ever with the aromatase enzyme. These modifications are also responsible for Trenbolone’s extremely enhanced andrognic strength (its ability to bind at a much greater strength to the androgen receptor) and its ability to remain highly resistant to metabolic breakdown in the body.
Properties of Trenbolone
The chemical modifications described above result in Trenbolone becoming dramatically more potent of an androgen and an anabolic than its progenitor hormone Nandrolone, or even Testosterone. Testosterone is used as the baseline reference by which all other anabolic steroids are measured against and compared to (much like how the Celsius temperature scale utilizes the boiling and freezing point of water as the base reference for temperature measurement). As such, we can put Trenbolone’s anabolic and androgenic strength into perspective by comparing it to Testosterone. Testosterone possesses an anabolic and androgenic rating of 100 each, respectively. Trenbolone holds an anabolic and androgenic rating of both 500 each, respectively. The modification responsible for making Trenbolone five times stronger than Testosterone is its two double bonds at carbons 19 and 11. Furthermore, for better understanding and perspective, every potential Trenbolone user must realize that in order to achieve the equivalent strength of 200mg of Trenbolone, one would have to administer 1,000mg of Testosterone. In order for an individual to achieve the strength of 500mg of Trenbolone, the equivalent of 2,500mg of Testosterone would be required.
This establishes an extremely important and interesting point for every user to remember: Trenbolone is an extremely strong anabolic steroid (the strongest conventionally available) and it is very evident from the numbers presented that in order to achieve impressive performance and physique changes, large doses of Trenbolone are not necessary and small amounts can carry gains a long way. Therefore, it must be said that when it comes to Trenbolone, a little goes a long way.
In terms of its metabolism, it has been previously mentioned that Trenbolone is totally resistant to the aromatase enzyme (which is the enzyme that is responsible for the conversion of aromatizable androgens into Estrogen). Therefore, Trenbolone holds zero Estrogenic activity as it cannot convert into Estrogen in any amount. Trenbolone also is completely resistant to the 5-alpha reductase enzyme, which is the enzyme responsible for the reduction of Testosterone into the much stronger androgen Dihydrotestosterone (DHT). Trenbolone here as well is immune from interaction with the 5-alpha reductase enzyme and cannot convert into DHT. However, it must be understood that Trenbolone in its own right is a very androgenic hormone (remember that Trenbolone holds an androgenic rating of 100 versus Testosterone’s androgenic rating of 100).
The extreme strength of the anabolic nature of Trenbolone alongside the fact that it cannot convert into Estrogen are all factors that enable Trenbolone to be such a versatile and flexible anabolic steroid – it can provide massive strength and lean mass gains in a bulk, and can also be utilized for cutting and fat loss phases as well. These features certainly crush the age-old rumor that Trenbolone is only useful for fat loss or cutting and/or for a pre-competition phase. These rumors have circulated from individuals within the anabolic steroid using community who are uneducated on Trenbolone and its features. This is also very supportive of the fact that there is no reason for utilizing Trenbolone at extremely high and unnecessary doses. This is especially true if an individual is a beginner to Trenbolone use.
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